Exosomes

Exosomes are a ground-breaking, new way to stimulate deep skin renewal. Exosomes plus our tailored med spa treatments can support hydration, promote an even tone and complexion, and improve the overall condition of your skin. This advanced skincare therapy improves the appearance of crepey skin, hyperpigmentation, wrinkles, elasticity, pore size, and healing after procedures. We understand that you want to look and feel your best; who doesn’t? We offer this exciting new treatment to help our patients in the San Francisco Bay Area do just that. Help your skin heal and look healthy long-term with exosomes. ExoElixir Dermal Fibroblast Exosomes have growth factors that are super-charged to regenerate the properties that keep our skin healthy and youthful.

Plastic Surgery Specialists offers patients in Marin County and the Bay area the newest, most innovative treatments. Schedule a consultation to learn more about adding topical exosomes to one of our tailored skin care treatments. Contact us at (415) 384-9787 to book a consultation or fill out our inquiry form.

Visit our blog to learn more about our different skin treatments, and the many other services we offer.

More About Exosomes

Time takes a toll on our physical appearance, which is why fighting signs of aging and maintaining the skin’s health are critical to maintaining the feeling and appearance of youth and vitality. Dull, blemish-prone skin and rough-textured skin can be treated with specialized med spa treatments to improve skin health and aesthetics. In addition, the latest nanoparticle technology can help enhance cell-to-cell communication and support a healthier, younger-looking complexion.

As scientists learn more and more about the ability of exosomes to improve skin health, new technologies are being developed to harness their power. Science has come a long way since exosomes were first discovered in the 60s, and we can now use them topically to improve the appearance of our skin. ^[1] Exo Elixir is a one-time treatment that doesn’t require a blood draw. Rather than utilizing your own growth factors, Exo Elixir contains newer, younger growth factors for maximum effect.

Exosomes have been shown to play a variety of functions; they are important for wound healing and skin and hair health. Furthermore, they may be utilized with skincare products and procedures that improve the look and health of the skin. They help diminish hyperpigmentation and hydrate the skin, while speeding up the healing process after a procedure. Microneedling treatments, for example, can be enhanced with exosomes thanks to the tiny microchannels formed by the needles, which can transport exosomes directly into the skin to aid in regeneration. So, what exactly are exosomes, and how can they benefit the skin?

What Are Exosomes?

Exosomes are generated by almost every cell type in the body and are released when the cell fuses with the plasma membrane. They’re essential for several reasons, but their primary function is to help with cell-to-cell communication. For the body to maintain a healthy status, the cells must be able to communicate effectively. A stall in information flow, such as following an injury or sickness, can cause an imbalance in the body; this is where exosomes can play a vital role.

Exosomes can “communicate” like this because they can transfer their contents, including proteins, lipids, RNA, and other vital materials, to the cells; this allows for two-way communication between cells, which is essential for maintaining a healthy balance in the body. Exosomes have been proven to promote tissue generation, which can help the body remodel and heal. ^[2] They’re part of a family of particles called extracellular vesicles (EVs). EVs are tiny sac-like structures that contain fluid and play a vital role in cell communication and intercellular transport.

Materials Shared by Exosomes

Fibroblasts

There are many different types of cells in connective tissue, but fibroblasts are the most common and essential for wound healing and tissue regeneration. ^[3] Unfortunately, we lose 1% of our dermal fibrolasts each year. Fibroblasts produce the protein collagen, which is responsible for keeping our skin firm and supple.

Growth Factors

Growth factors are signaling proteins necessary for cell proliferation, cell differentiation, and cell survival; they regulate many biological processes and are essential for wound healing and tissue regeneration.

Cytokines

Cytokines are a type of protein involved in cell signaling; they’re important for regulating immune and inflammatory responses.

Benefits of Exosomes

At Plastic Surgery Specialists, we are constantly assessing new technologies to offer the best choices for our patients. We feel this revolutionary treatment can truly renew skin and hair growth. Advantages of exosome therapy with ExoElixir include:

Can Exosomes Help With Atopic Dermatitis?

Atopic dermatitis, or eczema, is a chronic inflammatory skin condition affecting millions worldwide. The exact cause of eczema is unknown, but it’s thought to be due to a combination of genetic and environmental factors. Unfortunately, treatment options are limited, and there is no cure for eczema.

Fortunately, exosomes have been shown to play a role in the pathogenesis of eczema. They’re able to modulate the immune response and have anti-inflammatory effects. A study published in 2016 found that topical application of exosomes can significantly improve eczema symptoms. The study found that exosomes could reduce inflammation and increase skin barrier function.

What’s the Difference Between Exosomes and PRP?

It’s all about the numbers! 

PRP has less than 15 growth factors, while ExoElixir contains 380. This means that PRP, while beneficial, can have an inconsistent effectivity, since the limited number of growth factors can’t repair and regenerate the dermal fibroblasts as efficiently as exosomes can.

And, PRP only delivers 8 forms of collagen, while ExoElixir delivers 30 forms of collagen.

Exosome Growth Factor Products

We’ve chosen the best Exosome products we can find to introduce our patients to this phenomenal and regenerative product. Exosomes are growth factors that help heal and rejuvenate skin on a cellular level. Below are the choices for both take-home skincare and add-on serums for our micro-needling treatments.

ELEVAI Enfinity Regenerative SERUM

DAILY REPAIR + POST-TREATMENT

Enfinity Serum is an effective blend of ELEVAI exosomes combined with stem cell growth factors and the most effective skincare ingredients available to support skin health repair. This serum provides skin rejuvenation and with repeated use, generates healthier, more balanced skin health – offering results you can see and feel. Ingredients include calming cytokines, copper peptides, hydrating hyaluronic acid, and protective vitamin C.

AQ Active SERUM

AQ Active Serum applies patented Growth Factor (GF) Technology, to transform the skin. This GF Technology utilizes high-purity fibroblast growth factors; the fibroblasts are responsible for the natural maintenance of skin cells. Daily application of these growth factors in AQ Active Serum can dramatically reduce the appearance of fine lines and wrinkles, correct hyperpigmentation, and repair collagen. The serum formulation includes a cocktail of beneficial peptides that work to help restore texture, skin tone and hydration. The results are truly amazing.

EXO ELIXIR TREATMENT

This in-office treatment regenerates at a cellular level. We use it subdermally for hair growth, and post-micro-needling for an incredible boost to skin health and regeneration. It contains dermal fibroblast stem cells responsible for keeping the connective tissue intact. This prevents the skin from sagging, leading to firmer younger looking skin. The stem cells dramatically decrease recovery time and alleviate post-treatment symptoms from aesthetic procedures. Some benefits include:

EXOGROW HAIR TREATMENT

THE EVOLUTION IN HAIR RESTORATION

Exosome therapy is a less expensive alternative to hair replacement surgery. This non-invasive treatment option increases hair thickness, fills in a receding hairline, and treats baldness and severe alopecia.

Personal Consultation

Your consultation with Plastic Surgery Specialists will help you not only discover more about the best ways to fight signs of aging but also rapidly transform your skin’s health. Our beautiful Greenbrae office offers comprehensive skin treatment services for many common skin conditions. Our team of skin care specialists appreciate that great skin treatments go a long way, but science goes even further. For example, our services can treat the following:

During your consultation, you can discuss the procedures that interest you most. You may also learn whether exosome therapy may be used to improve your cosmetic results and strengthen your skin. We will determine which treatments are ideal for your skin and personal aesthetic goals based on a thorough skin examination.

Rejuvenating Skin Treatments

People come from all over the Bay Area and beyond to visit Plastic Surgery Specialists. Whether you want to reduce the appearance of wrinkles, heal scars or blemishes, improve your skin texture, or just make your skin look brighter and more hydrated, our team can help you out!

Topical exosomes can be added to the following skin treatments:

ProCell Microchanneling Therapy

By puncturing the skin with fine needles, ProCell Microchanneling Therapy encourages more profound regeneration within your tissue; this collagen production results in fewer wrinkles and a more youthful appearance. In addition, adding exosomes to your microneedling treatment can double down on collagen production and achieve even better results.

Hydrafacial MD

Hydrafacial uses patented technology to cleanse, exfoliate, and replenish your skin in one short visit; this facial treatment is excellent for people with busy schedules who still want to enjoy beautiful skin. Adding exosomes to your Hydrafacial will help improve results even more, providing you with hydration, radiance, and smoothness that lasts.

PRP/Vampire Facial

Platelets are essential for healing, and Vampire Facials use these natural substances to encourage collagen production, faster recovery, and softer skin. By adding exosomes to your PRP facial, you can enjoy even better results, as exosomes will help to deliver the platelets more effectively.

Diamond Glow

The Diamond Glow experience is unlike any other. The device uses a closed-loop vacuum with a diamond tip to exfoliate and eliminate dead skin cells while delivering SkinMedica serums to enhance skin texture, tone, and moisture. This treatment can help with acne scarring, wrinkles, uneven skin texture, and other minor flaws in the epidermis (outer layer of the epidermis).

The results are intensified when you add exosomes to your Diamond Glow experience. Not only will your skin be exfoliated and hydrated, but it will also receive a much-needed boost of collagen and elastin; this treatment is perfect for those who want to improve the overall appearance of the skin.

Chemical Peel

A chemical peel uses a solution to remove the top layers of dead skin cells, revealing the softer, smoother skin underneath. Chemical peels can be used to improve the appearance of wrinkles, fine lines, age spots, and other blemishes. PSS offers a variety of peels, including superficial, medium, and deep peels, as well as the Cosmelan Chemical Peel for Hyperpigmentation. Add exosomes to your chemical peel and watch the years melt away.

What is the Cost of Exosomes in the Bay Area?

Ask about adding ExoElixir to your skin procedure. Also, please inquire about exosomes if you’re considering microneedling, aesthetic laser treatment, chemical peels, PRP, or other facial skin rejuvenation services. Call (415) 384-9787 or fill out a simple inquiry form to book your consultation with Plastic Surgery Specialists.

We look forward to treating your skin!

References

1. Yang GH, Lee YB, Kang D, et al. Overcome the barriers of the skin: exosome therapy. Biomaterials Research. 2021;25(1). http://www.doi.org/10.1186/s40824-021-00224-8 
2. Dinescu S, Dobranici A, Tecucianu R, et al. Exosomes as Part of the Human Adipose-Derived Stem Cells Secretome- Opening New Perspectives for Cell-Free Regenerative Applications. Advances in Experimental Medicine and Biology. Published online 2020:139-163. https://www.doi.org/10.1007/5584_2020_588 
3. Dick MK, Miao JH, Limaiem F. Histology, Fibroblast. PubMed. Published 2020. https://www.ncbi.nlm.nih.gov/books/NBK541065/#:~:text=The%20fibroblast%20is%20one%20of 
4. Shin KO, Ha DH, Kim JO, et al. Exosomes from Human Adipose Tissue-Derived Mesenchymal Stem Cells Promote Epidermal Barrier Repair by Inducing de Novo Synthesis of Ceramides in Atopic Dermatitis. Cells. 2020;9(3):680. http://www.doi.org/10.3390/cells9030680